WASHINGTON (AP) — House Republicans have launched their most ambitious, pro-business effort yet to rein in Obama administration regulators, triggering a furious debate over the value of new rules for clean air, workplace safety, children’s toys and many other categories.

The House was set to vote Friday on the second of two anti-regulation bills, legislation that would impose potentially stifling procedures on federal regulators. Republicans argue that avoiding expensive new regulations would aid businesses in hiring workers, while Democrats counter that Americans’ health and safety would be jeopardized.