Tag: health news
How The U.S. and U.N. Created A Major Cholera Outbreak In Haiti

How The U.S. and U.N. Created A Major Cholera Outbreak In Haiti

Scientists say the warming of the ocean due to human-made climate change has intensified mega-storms like Hurricane Matthew, which recently tore through the Caribbean and parts of the United States, killing more than 1,000 people in Haiti alone, according to some estimates.

Now, with 1.4 million Haitians in need of emergency assistance, Haiti is bracing for another human-made disaster: a resurgence of its cholera outbreak, which dates to the aftermath of the catastrophic 2010 earthquake.

It took six years for the United Nations to publicly acknowledge what the scientific community has long known: the cholera epidemic was introduced to Haiti by U.N. peacekeepers, originating at one of the global organization’s camps in the upper Artibonite River valley, and from there, spreading through the country’s crumbling water system. The global failure to swiftly acknowledge the source of the outbreak and take aggressive action to eradicate it, has left the country vulnerable to the new uptick in infections.

The Pan American Health Organization (PAHO) said last week that it expects “an important upsurge in cholera cases in Haiti after Hurricane Matthew, given the context of flooding and the storm’s impact on water and sanitation infrastructure.”

“Water and sanitary conditions are expected to worsen due to the effects of Hurricane Matthew,” said Ciro Ugarte, the head of PAHO’s Program on Health Emergencies. “Efforts were already being directed to control the current epidemic of cholera and the high levels of vector-borne and water-borne diseases, but there is a limited capacity to respond to those challenges.”

Dominique Legros, cholera expert for the World Health Organization, told reporters Tuesday that there have been roughly 200 new cases after Hurricane Matthew. “It is more than usual. I know it is a sharp increase compared to [the] usual figures,” he said.

While cholera is preventable and easily treated under the right conditions, it has torn a devastating path through Haiti. Since October 2010, there have been more than 790,000 reported cases, and more than 9,300 people have been killed by the disease, according to PAHO. At its worst point in 2011, the epidemic was infecting 6,766 people every week. While cases continue, they have declined significantly, from 300,000 in 2011 to roughly 36,000 in 2015.

An expert panel convened by U.N. Secretary-General Ban Ki-Moon concluded in a 2011 report that cholera spread from a U.N. peacekeepers camp in the upper Artibonite River valley to the Meye Tributary system, which is used by “tens of thousands” of people for “washing, bathing, drinking and recreation.” Poor sanitation infrastructure caused human waste to contaminate the river system, leading to Haiti’s first cholera case in more than 100 years.

Numerous other scientific studies also pointed toward the role of the peacekeepers. Julianna LeMieux, senior fellow in molecular biology at the American Council on Science and Health, recently wrote, “The scientific community has known for years that the U.N. brought cholera to Haiti.”

Yet it was not until six years after the U.N. report came out—in August 2016—that the global institution made a nod to responsibility for its role in spreading the outbreak in Haiti, with spokesperson Farhan Haq proclaiming that “the U.N. has become convinced that it needs to do much more regarding its own involvement in the initial outbreak and the suffering of those affected by cholera.”

This statement fell short of a full apology for the years that the U.N. spent denying its role in introducing the outbreak. Meanwhile, the U.N. continues to fight legal efforts by Haitian victims to win restitution, claiming immunity from a complaint filed on behalf of 5,000 victims of cholera. According to the Institute for Justice and Democracy in Haiti, the victims are demanding that the United Nations, “Install a national water and sanitation system that will control the epidemic; compensate individual victims of cholera for their losses; and issue a public apology from the United Nations for its wrongful acts.”

Dan Beeton, international communications director for the Center for Economic and Policy Research, told AlterNet that the new wave of cholera infections could have been avoided “had there been a serious effort to eradicate cholera. What we’ve seen since the epidemic started six years ago is a focus on treatment during the rainy season when infections go up, but during the dry season people back off, so the epidemic remains.”

In a prescient warning, CEPR researchers Jake Johnston and Keane Bhatt wrote in 2011 that “health interventions launched to fight cholera have been hobbled by the initial missteps made in the wake of the epidemic. The international community underestimated the virulence of the outbreak; the U.N. initially denied responsibility for its introduction; and there was hesitation in investigating the circumstances surrounding its appearance.”  At the same time, the U.N.-backed National Plan for the Elimination of Cholera in Haiti, 2013-2022, remains woefully under-funded, with the medium-term plan only 22 percent pledged and under 11 percent disbursed.

Some U.S. lawmakers are directing criticism toward the U.N., with 158 members of Congress who wrote a letter to John Kerry in June calling on the State Department to “immediately and unreservedly exercise its leadership to ensure that the United Nations take concrete steps to eliminate the cholera epidemic introduced to Haiti in 2010 by waste from a U.N. peacekeeper camp, and to comply with its legal and moral obligations to provide cholera victims with access to an effective remedy.”

However, this finger-pointing deflects from the central role that the U.S. played in setting the stage for the post-earthquake crisis, by undermining efforts to improve the country’s public water infrastructure. A paper published 2013 by the journal of the National Institutes of Health found that “Haiti has the lowest rates of access to improved water and sanitation infrastructure in the western hemisphere. This situation was likely exacerbated by the earthquake in 2010 and also contributed to the rapid spread of the cholera epidemic that started later that same year.”

The U.S. government bears responsibility for keeping Haiti’s water system in a state of disrepair. According to a report released in 2008 by Partners In Health, Zanmi Lasante, the Center for Human Rights and Global Justice and the Robert F. Kennedy Memorial Center, the U.S. government clandestinely undermined a $54 million loan granted in 1998 by the Inter-American Development Bank to the Haitian government to improve its outdated water system. According to the report, the U.S. was motivated by the desire to destabilize Haiti’s elected government under then-President Jean-Bertrand Aristide.

However, the report notes that the root causes date back further. “Continual requirements to pay its debilitating debts—which date back to its early days of independence, when Haiti was essentially forced to purchase its freedom from the French for an exorbitant sum, and which has further amassed during two centuries of political turmoil, foreign occupation, and corruption—have left the Haitian government unable to funnel its limited resources into social infrastructure programs like water and sanitation systems, with catastrophic effects on the health and well-being of the Haitian people,” the report states.

Reprinted by permission from Alternet. Sarah Lazare is a staff writer for AlterNet. A former staff writer for Common Dreams, she coedited the book About Face: Military Resisters Turn Against War. Follow her on Twitter at @sarahlazare.

IMAGE: People are treated at a cholera treatment center at a hospital after Hurricane Matthew passed through Jeremie, Haiti, October 11, 2016. REUTERS/Carlos Garcia 

Ebola Virus Vaccine Developed By Bird Flu Scientist

Ebola Virus Vaccine Developed By Bird Flu Scientist

By Karen Herzog, Milwaukee Journal Sentinel (TNS)

Another vaccine has joined the race against the often fatal Ebola virus, and this one was developed by a group led by a University of Wisconsin-Madison scientist internationally known for his bird flu research.

The whole virus vaccine that Yoshihiro Kawaoka and his colleagues developed was constructed using a novel experimental platform, and it has been shown to effectively protect monkeys exposed to the Ebola virus at a top biosafety-level National Institutes of Health laboratory in Montana, according to an article published Thursday in the prominent journal Science.

This vaccine differs from other Ebola vaccines in development because, as an inactivated whole virus vaccine, it can prime the host immune system with the complete range of Ebola viral proteins and genes, which makes it more likely to trigger a robust immune response, according to a news release from UW-Madison.

“In terms of efficacy, this affords excellent protection,” said Kawaoka, a professor of pathobiological sciences in the UW-Madison School of Veterinary Medicine who has been working on the Ebola vaccine for years, and also holds a faculty appointment at the University of Tokyo.

There are no proven treatments for Ebola or vaccines to prevent individuals from becoming infected. Ebola, previously known as Ebola hemorrhagic fever, is a rare and deadly disease first discovered in 1976 near the Ebola River in what is now the Democratic Republic of the Congo.

Ebola has claimed more than 10,000 lives in a current outbreak in Guinea, Liberia, and Sierra Leone. Symptoms include fever, severe headache, muscle pain, fatigue, diarrhea, vomiting, stomach pain, and unexplained bleeding or bruising.

Whole virus vaccines have long been used to successfully prevent such serious diseases as polio, hepatitis, and human papillomavirus-mediated cervical cancer.

The vaccine developed by Kawaoka’s group does not yet have the backing of a manufacturer, and has not been tested in people. Human trials are expensive and complex, costing millions of dollars.

Four other Ebola vaccines in development recently advanced to the clinical trial stage in humans.

An efficacy trial for an Ebola vaccine developed by the Public Health Agency of Canada launched Wednesday in a community in Guinea where Ebola spread. About 10,000 people are expected to receive that vaccine, which reportedly has shown positive results in smaller safety trials and is backed by NewLink Genetics and Merck.

Kawaoka said the experimental platforms on which the four other vaccines were developed have drawbacks in terms of safety and delivery.

The vaccine with UW-Madison ties was constructed on an experimental platform first devised in 2008 by Peter Halfmann, a research scientist in Kawaoka’s lab.

That experimental platform allows researchers to safely work with the virus because a key gene is deleted, according to the Science report describing the vaccine’s development. The Ebola virus uses that gene, known as VP30, to make a protein required for it to reproduce in host cells. Like most viruses, Ebola depends on host cells to grow and become infectious.

By engineering monkey kidney cells to express the deleted VP30 protein, the virus could be safely studied in the lab and be used as a basis for devising a whole virus vaccine. The vaccine also was chemically inactivated using hydrogen peroxide, the Science report noted.

Early attempts to devise an inactivated whole virus Ebola vaccine through irradiation and the preservative formalin failed to protect monkeys exposed to the Ebola virus and were abandoned, according to Kawaoka.

The Ebola vaccine study conducted by Kawaoka’s group was supported by the National Institutes of Health and Japanese Health and Labor Sciences Research Grants.

(c)2015 Milwaukee Journal Sentinel, Distributed by Tribune Content Agency, LLC

Photo: AFP Photo/Zoom Dosso

Indiana Fights Major HIV Outbreak In Rural County

Indiana Fights Major HIV Outbreak In Rural County

By Michael Muskal, Los Angeles Times (TNS)

As a nurse and manager of the only medical office in Austin, Ind., Jeanni McCarty finds herself at the heart of the state’s worst-ever outbreak of HIV, so bad that on Thursday the governor declared a heath emergency.

McCarty, 42, grew up in Austin, but she scarcely recognizes it now.

“It’s not what it used to be,” said McCarty, who still lives in Scott County, in the southeast corner of Indiana. She described a region where many people live in poverty with limited prospects of jobs and a “very, very serious drug problem that has made us the epicenter of the HIV outbreak.”

The Scott County outbreak has been linked to the illegal use of contaminated syringes. On Thursday, Gov. Mike Pence authorized a short-term exchange to fight the spread of HIV, an exception to Indiana’s conservative anti-drug policy that bars needle-exchange programs that trade dirty needles for uncontaminated ones.

“This is all hands on deck. This is a very serious situation,” the Republican governor said at a news conference.

“Scott County is facing an epidemic of HIV, but this is not a Scott County problem; this is an Indiana problem,” Pence said, announcing the health emergency and executive order.

The order will run for 30 days but Pence can extend it. In addition to the needle exchange, the order sets up a command center to coordinate HIV and substance-abuse treatments, according to the state. The state is also establishing a public awareness program to explain safe sex and needle disposal and a hotline to get HIV testing and treatment.

Scott County, about 30 miles north of Louisville, Ky., is a rural area of about 24,000 people. Running through the area is Interstate 65, a broad highway that brings in drugs — and customers for prostitutes, who face a double danger.

The human immunodeficiency virus is spread among people through blood and other bodily fluids, and is associated with risky sexual activities and the use of contaminated needles. HIV attacks an individual’s immune system and eventually leads to AIDS, or acquired immunodeficiency syndrome.

Typically, Scott County sees fewer than five HIV cases a year, but 71 cases have already been confirmed since late January, and at least nine more cases have been given a preliminary positive status, according to Amanda Turney, a spokeswoman for the State Department of Health. It is the worst such outbreak in the state and probably the worst in the nation, though national statistics are unavailable, she said.

The number of cases is expected to increase. Health officials say they are trying to contact as many as 100 people tied to those with confirmed HIV infections.

“The number will grow,” McCarty agreed in a telephone interview. “We’re doing more testing already and we have people here waiting on line to be tested.”

Foundations Family Medicine is the only medical office in Austin. McCarty says it has one doctor, three nurse practitioners, five nurses, and two medical assistants to care for the approximately 12,000 patients who have come in.

She says the HIV outbreak had been expected.

“It’s been a long time coming,” McCarty said. “About three to four years ago, we noticed a big increase in the number of hepatitis C cases.” Hepatitis C is also spread through blood and is associated with illegal drug use.

Since then, almost all of the confirmed HIV cases have been from Austin, a city of about 4,200. Given how quickly it has spread, more cases are expected in the coming weeks.

Some help is on the way: The area is getting its first specialist in infectious disease. Patients are being treated at no charge once they test positive for HIV.

“This has been hard to swallow,” McCarty said of the outbreak.

“A lot of the problem comes from poverty,” she said. “These people don’t have education to get jobs. Resources are so limited.”

(c)2015 Los Angeles Times, Distributed by Tribune Content Agency, LLC

New York Latest U.S. State To Allow Medical Marijuana

New York Latest U.S. State To Allow Medical Marijuana

New York (AFP) – Governor Andrew Cuomo on Monday signed a bill making New York the 23rd U.S. state to legalize marijuana for medical use.

The state’s law requires a medical prescription for marijuana and limits its use to help treating patients with cancer, HIV, Lou Gehrig’s disease, Parkinson’s, epilepsy and a few other illnesses.

Patients also must agree to sign up for the medical marijuana program. The number of distributing centers is small, and treatment cannot exceed 30 days.

“New York State has a proud history of being in the forefront of many advances in medicine,” Cuomo said. “We are here to help people and if there’s a medical advancement, we want to help bring it to New Yorkers.”

“This legislation gets us the best medical marijuana has to offer, in the most protective, controlled way possible,” added Cuomo, who once opposed medical marijuana.

Two U.S. states have legalized marijuana consumption for adults, with no medical requirement: Colorado and Washington.

AFP Photo/Frederic J Brown